首页> 外国专利> Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid, especially for use as hypolipidemic agents, processes for their preparation, pharmaceutical compositions comprising them, tetrahydropyran-2,3,5-triones useful in the preparation of the said derivatives and a process for preparing these tetrahydropyran-2,3,5-triones

Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid, especially for use as hypolipidemic agents, processes for their preparation, pharmaceutical compositions comprising them, tetrahydropyran-2,3,5-triones useful in the preparation of the said derivatives and a process for preparing these tetrahydropyran-2,3,5-triones

机译:4,5-二氢-4-氧杂呋喃-2-羧酸的衍生物,特别是用作降血脂药,其制备方法,包含它们的药物组合物,可用于制备所述化合物的四氢吡喃-2,3,5-三酮衍生物和制备这些四氢吡喃-2,3,5-三酮的方法

摘要

{PG,1 Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid characterized by having two substituents at position 5 and in addition being optionally further substituted at position 3 with a lower alkyl group, as well as esters therefor are disclosed. The foregoing compounds are useful hypolipidemic agents in a mammal. Novel methods for the preparation of these compounds also are disclosed.
机译:{PG,1的酯,其特征在于4,5-二氢-4-氧杂呋喃-2-羧酸的衍生物,其特征在于在位置5具有两个取代基,并且任选地在位置3处进一步被低级烷基取代。披露。前述化合物在哺乳动物中是有用的降血脂药。还公开了制备这些化合物的新方法。

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