(1) benzopyrano 2h and 2h (1) benzothiopyrano cd four, three, two indazol - n - oxides, process for their preparation and medicines containing them

摘要

1431617 N-oxides of benzopyrano- and benzothiopyrano - indazole derivatives PARKE DAVIS & CO 15 July 1974 [16 July 1973] 31319/74 Heading C2C The invention comprises compounds of formula and their acid addition salts, wherein A is C 2-4 alkylene; RSP1/SP and RSP2/SP are each C 1-4 alkyl or NRSP1/SPRSP2/SP is a C 4 -C 6 ring polymethyleneimine possibly substituted by alkyl totalling # C 2 ); W is Me or ZOCH 2 , where Z is H or C 1-8 acyl; Y is S or O; and one of Q, R is H, while the other is H, halogen or C 1-4 alkoxy. These compounds are prepared by N-oxidation of the corresponding tertiary amines. Parasiticidal compositions having particular reference to the treatment of schistosome infections of mammals comprise compounds of the above formula, and may be administered orally or parenterally.