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DIHYDROPYRIDAZONES, THEIR PREPARATION AND MEDICINES CONTAINING THEM AND DIHYDROPYRIDAZONES FOR USE IN MEDICAL TREATMENTS

机译:双氢哒嗪酮,其制备方法及含有它们的药物和用于医疗的双氢哒嗪酮

摘要

6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I IMAGE I where R1 is hydrogen or alkyl of 1 to 3 carbon atoms and R2, if R1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or beta -haloethyl or, if R1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manufacture, and therapeutic agents which contain, as the active ingredient, a compound of the formula I, where R2 may also be halomethyl or alpha -haloethyl if R1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thromboembolic disorders.
机译:式I I的6-(对-酰基氨基苯基)-4,5-二氢吡唑-3-酮其中R1是氢或1-3个碳原子的烷基,R2(如果R1是氢)是卤素取代的烷基1-6个碳原子或β-卤代乙基,或如果R 1是1-3个碳原子的烷基,则是1-6个碳原子的卤素取代的烷基,它们的制备和含有作为活性成分的治疗剂式I的化合物,其中如果R 1是氢,则R 2也可以是卤代甲基或α-卤代乙基。这些化合物可用作抗高血压药,并用于血栓栓塞性疾病的预防和治疗。

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