NOVEL DIBENZ (B,F) OXEPIN AND DIBENZO (B,F) THIEPIN COMPOUNDS AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

The invention provides dibenz [b, f] oxepin and dibenzo [b, f] thiepin derivatives of the formula …CHEM… wherein X is an oxygen or sulfur atom, each of R1 and R2 is a hydrogen atom or a methyl group, and R3 is a hydrogen atom or a 2-(2-hydroxyethoxy) ethyl group; provided that when R1 is a hydrogen …CHEM… atom, the group -CHCOOR3 is a group other than a I-carboxyethyl group, and when X is a sulfur atom, both R1 and R2 are methyl groups; …??and pharmaceutically acceptable salts of said compounds in which R3 is a hydrogen atom. Compositions of said compounds or salts and processes for their preparation are also provided. These compounds and salts thereof have excellent anti-inflammatory, analgesic and antipyretic activities.