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process for the production of derivatives of gamma butyrolactone, which is myocardiebeskyttelsesmidler with an antiarrhythmic effect
process for the production of derivatives of gamma butyrolactone, which is myocardiebeskyttelsesmidler with an antiarrhythmic effect
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机译:γ-丁内酯衍生物的制备方法,它是具有抗心律不齐作用的心肌酶
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摘要
The present invention relates to the products of general formula: IMAGE (I) in which: R represents a straight or branched alkyl group having from 2 to 5 atoms of carbon, or the group IMAGE represents a morpholino or piperidino group possibly substituted by 1 or 2 methyl groups; n=2 or 3; R1 and R2 considered independently each represent hydrogen or a lower alkyl group (1 to 4 carbon atoms) or R1 and R2 taken together represent a (CH2)m group where m=4 or 5, R3 being equal to H or R1 is H and R2 and R3 considered together represent (CH2)p where p is 3 or 4 the butyrolactone cycle substitutes the pyridyl group in 2', 3' or 4' position, the salts, isomers and mixtures of isomers of said products; and to a process for preparing said products and to the myocardium-protecting drugs containing same.
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