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platinum complexes diamminici, process for their preparationprocess to prepare a medical composition containing these complexes diamminici platinum - for the treatment of cancer, nonche'composition so produced.
platinum complexes diamminici, process for their preparationprocess to prepare a medical composition containing these complexes diamminici platinum - for the treatment of cancer, nonche'composition so produced.
This invention relates to novel platinum compounds, a method for the preparation thereof, a pharmaceutical composition using the novel compounds and a method for the treatment of cancer using the pharmaceutical composition, wherein the platinum-(II)-diamine complexes are characterized by the formula IMAGE wherein R1 and R2 are both ethyl or together with the carbon atom, to which they are bonded, a cyclohexyl group, R3 and R4 are both a hydrogen atom and X is a malonate group, an ethylmalonate group, a hydroxymalonate group, a carboxyphthalate group, a bischloro acetate group, a cyclobutane-1,1-dicarboxylate group, a dinitrate group or an oxalate group or a sodium salt of these groups.
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