4,4-DISUBSTITUTED SPIRO-1,4-DIHYDROPYRIDINE, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN INTERMEDIATE PRODUCT.

摘要

The invention relates to 4,4-disubstituted spiro-1,4-dihydropyridine compounds of formula (I). Also included in the invention are methods for producing the compounds of formula (I) by (a) cyclizing a compound of formula (II) in the presence of a base or (b) reducing a sulphinyl compound of formula (I) by means of Raney nickel. The compounds of formula I are intermediates and can be converted to sulphur-free compounds of formula (III) which are known to be useful for treating circulatory illnesses.