14,15-dihydro-14b-hydroxi obtaining procedure (3x, 16x) -baramenin-14-carboxilico-meter ester .. (Machine-translation by Google Translate, not legally binding)

摘要

Procedure for obtaining the methyl ester of the acid 14,15-dihydro-14 ~ j-hydroxy- (3 ~ c, 16 ~ c) -berbunamenine-14-carboxylic. Consists of the hydrogenation of alcohol tabersonine at pressure between 100 mm hg and 3 atm, in the presence of catalyst of paladium on carbon of 5%, in methanolic medium; following the oxidation of the vincadiformine obtained, in become, with an organic perception; extraction of bencenic dissolution with acetic acid at 60%, with acetic acid at 10% and with water; mix of the extracts; catalytic hydrogenation in the presence of paladium over carbon; separation of catalyst by filtration; adjusting ph a 9 and extraction with methylene chloride. This composite has pharmacological applications to establish and maintain a normal blood flow. (Machine-translation by Google Translate, not legally binding)