首页> 外国专利> Agents for the detection of esterolytic and/or proteolytic enzymes; and phenoxy-amino acids and phenoxy-peptide esters suitable as substrates therefor, process for their production and their use in producing the agents

Agents for the detection of esterolytic and/or proteolytic enzymes; and phenoxy-amino acids and phenoxy-peptide esters suitable as substrates therefor, process for their production and their use in producing the agents

机译:用于检测酯水解酶和/或蛋白水解酶的试剂;以及适合用作其底物的苯氧基氨基酸和苯氧基肽酯,其制备方法及其在制备试剂中的用途

摘要

Esters and agents including the esters, useful as substrates for esterolytic and/or proteolytic enzymes, said esters being compounds of the general formula: IMAGE in which R''1, R''2, R''3 and R''4, which may be the same or different, are hydrogen atoms or lower alkyl, lower alkoxy, alkylamino or dialkylamino radicals or in which two adjacent substituents can also represent a fused benzene ring, A is a residue of an amino acid or of a peptide and B is a nitrogen protective group conventional in peptide chemistry or derived therefrom; and the method of preparation and use.
机译:用作酯水解和/或蛋白水解酶底物的酯和包括酯在内的试剂,所述酯为通式为的化合物,其中R''1,R''2,R''3和R''在图4中可以相同或不同的是氢原子或低级烷基,低级烷氧基,烷基氨基或二烷基氨基基团,或者其中两个相邻的取代基也可以代表稠合的苯环,A是氨基酸或肽的残基B是肽化学中常规的或由其衍生的氮保护基;以及制备和使用方法。

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