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A 4-dimethylaminophenol-hydrochloride solution for painless intramuscular administration, and process for its preparation

机译:用于无痛肌内给药的4-二甲氨基苯酚盐酸盐溶液及其制备方法

摘要

A 4-dimethylaminophenol hydrochloride solution which on intramuscular administration causes no pain and induces no tissue necrosis, characterised in that it only contains small amounts of water or is water-free and in that the solvents used are physiologically tolerable lower alkanols, glycerol, glycols, glycol ethers, hydrophilic amides, esters, ethers, sulphones or sulphoxides or fatty acid esters or unsaturated oils or, in general, mixtures of such solvents, and also the process for the preparation of such pain-free injectable solutions by dissolving 4-dimethylaminophenol hydrochloride in the solvents mentioned and further processing to give injection solutions under the required hygienic conditions.
机译:肌内注射时不会引起疼痛且不会引起组织坏死的4-二甲氨基苯酚盐酸盐溶液,其特征在于它仅包含少量水或无水,并且所用溶剂为生理上可耐受的低级链烷醇,甘油,乙二醇,乙二醇醚,亲水性酰胺,酯,醚,砜或亚砜或脂肪酸酯或不饱和油,或通常是此类溶剂的混合物,以及通过溶解4-二甲基氨基苯酚盐酸盐制备此类无痛注射溶液的方法在上述溶剂中进行进一步处理,以在所需的卫生条件下提供注射溶液。

著录项

  • 公开/公告号EP0051163A3

    专利类型

  • 公开/公告日1983-02-16

    原文格式PDF

  • 申请/专利权人 DR. FRANZ KÖHLER CHEMIE KG;

    申请/专利号EP19810108102

  • 发明设计人 KÖHLER FRANZ DR.;

    申请日1981-10-09

  • 分类号A61K9/08;A61K31/135;

  • 国家 EP

  • 入库时间 2022-08-22 10:33:44

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