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Method of preparation of 4, l - benzoxazepines and their similar thia, novel products thus obtained and their use for the treatment of mental disorders
Method of preparation of 4, l - benzoxazepines and their similar thia, novel products thus obtained and their use for the treatment of mental disorders
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机译:制备4,l-苯并x氮平及其类似硫杂的方法,由此获得的新产品及其在治疗精神疾病中的用途
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摘要
4,1-Benzoxazepines and thia analogs thereof of the formula: IMAGE (wherein -A-B- is the following group: IMAGE +TR IMAGE (wherein R1 is hydrogen, C1 to C3 alkyl, or C7 to C9 aralkyl; R2 is C1 to C3 alkyl or C1 to C3 alpha -aminoalkyl; R3 is C2 to C6 dialkylamino; R4 is C2 to C6 dialkylamino or C5 to C7 alkylpiperazino; R5 is C1 to C3 alkyl; and Q is oxygen or sulfur); D is oxygen or sulfur; X is halogen or nitro; Y is hydrogen or halogen; and Z is hydrogen, C1 to C3 alkoxy, or C3 to C9 dialkylaminoalkoxy; with the proviso that when -A-B- is IMAGE Z is not hydrogen.) useful as novel central nervous system drugs are prepared by various synthetic routes.
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