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Tetra:hydro-pyridyl-indole derivs. - useful as antidepressant, antiparkinsonian and antiemetic agents
Tetra:hydro-pyridyl-indole derivs. - useful as antidepressant, antiparkinsonian and antiemetic agents
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机译:四:氢-吡啶基-吲哚衍生物。 -可用作抗抑郁药,抗帕金森病和止吐药
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摘要
R-substd. 1-R1-2-R2-3-(1,2,3,6-tetra hydro-4-pyridyl)-1H indoles of formula (I) and their acid-addn. salts are new. In (I) R is S, NH2 or CF3; R1 and R2 are H or 1-3C alkyl. (I) is e.g. 5-methylthio-3-(1,2,3,6-tetra hydro-4-pyridyl)-1H indole (Ia). (I) have antidepressant, antiparkinsonian and antiemetic activity at daily doses of 5-500 mg (p.o.).
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