New thiol polypeptide composed of a fragment of the toxin tetanus, its process of preparation and its applications

摘要

A new thiolated polypeptide compound derived from a fragment of tetanus toxin, the process for its obtention and its applications. This compound consists of the IIc fragment of tetanus toxin, having at least one -SH group either directly or indirectly bound thereto. It is usable as a specific neuropharmacological transport agent for transporting a medicine to the central nervous system, as a specific labelling agent for neuronal cells or for diagnosis purposes. It can be coupled with a medicine or a labelling agent.