ANGIOTENSIN TRANSFORMATION ENZYME INHIBITORS COMPRISING PHOSPHINEIC ACIDS SUBSTITUTED WITH AMINOALKYL AND RELATED RADICALS

摘要

COMPOUNDS OF DEVELOPED FORMULA: BR/ (CF DRAWING IN BOPI) BR/ IN WHICH R IS FOR EXAMPLE AN ARYULALKYL RADICAL, R AND R ARE EACH A HYDROGEN ATOM OR A LOWER ALKYL RADICAL, ARYLALKYL, BENZHYDRYL OR CH-OCR OR R IS A HYDROGEN OR UNRADICAL ATOM, LOWER OR PHENYL ALKYL; N is equal to 0 or 1; R is, for example, a radical of Formula NH (CH) in which M is an integer of 2 to 5, and X-OR is an imino-acid or amino-acid derivative. / P p THESE COMPOUNDS ARE INHIBITORS OF THE ANGIOTENSIN TRANSFORMATION ENZYME AND ARE THUS SUCCESSFUL FOR THE TREATMENT OF HYPERTENSION.