FOERFARANDE Foer FRAMSTAELLNING AV HYDROXIHALOGENBENSYLAMINDERIVAT MED HOSTSTILLANDE SEKRETOLYTISK OCH PRODUKTION AV YTAKTIVT AEMNE STEGRANDE Effect

摘要

The invention relates to a new process for the preparation of benzylamine derivatives having interesting pharmacological properties, in particular a secretolytic and antitussive activity as well as a stimulating effect on the production of the surfactant or antiatelectasis factor of the alveoli. The new process comprises the reaction of certain benzylamine derivatives with appropriate amines whereby amino group interchange occurs. Examples of the preparation of certain of the new benzylamine derivatives by means of the new process are given.