REMEDY FOR INFECTIOUS DISEASE WITH ASPERGILLUS

摘要

PURPOSE:To provide the titled drug having low side effects, and containing the antibody secreted from the hybridoma between the cell which can produce antibody against Aspergillus and the cell which can be subcultured for a long period in vitro. CONSTITUTION:The objective drug for the remedy of the infectious diseases with Aspergillus (Aspergillus fumigatus), contains an antibody secreted from hybridoma between the cell which can produce the antibody against Aspergillus and the cell which can be subcultured for a long period in vitro, or a novel substance obtained by chemically bonding said antibody with an antifungal agent (e.g. amphotericin, etc.) The antibody is monospecific and composed of single molecular species, and has extremely high titer per unit protein and high specific reactivity to antigen. Accordingly, the side effects caused by the attack of the antiboty to the tissue of the host can be eliminated by examining the tissue reactivity of the species to be administered, and selecting the agent free from cross-reactivity.