Novel, therapeutically active compounds have the following formula IMAGE in which Y denotes D-Val or D-Ala. The compounds can also be in the form of pharmaceutically acceptable acid addition salts. The compounds of the formula I are prepared by oxidising a corresponding tetradecapeptide, the two sulphydryl groups being converted into a disulphide bridge. The novel compounds can be used for inhibiting the release of growth hormones and for reducing intestinal motility.
展开▼