首页> 外国专利> Method for Preparing new derivatives (sulfoximino - alkoxy - or sulfimino) - 2 - (quinclin Ona, sulfoximino or sulfimino - 3,4-dihydro - alkoxy) - 2 - (quinclin Ona and sulfoximino or sulfimino - 33 - dialkyl - indolin-2-one

Method for Preparing new derivatives (sulfoximino - alkoxy - or sulfimino) - 2 - (quinclin Ona, sulfoximino or sulfimino - 3,4-dihydro - alkoxy) - 2 - (quinclin Ona and sulfoximino or sulfimino - 33 - dialkyl - indolin-2-one

机译:制备新衍生物的方法(磺肟基-烷氧基-或亚磺酰亚胺基)-2-(喹啉基Ona,磺基肟基或亚磺酰亚胺基-3,4-二氢-烷氧基)-2-(喹啉基Ona和磺基亚氨基或磺酰亚胺基-33-二烷基-吲哚啉-2 -一

摘要

Compounds of general formula I IMG (I) wherein n represents the number 0 or 1, A represents a methylene, vinylene or ethylene group optionally substituted by lower alkyl groups, B represents an alkylene group, R1 represents an optionally substituted alkyl, phenyl or naphthyl group, or a cycloalkyl or pyridyl group, and R2 represents a hydrogen atom or an acyl group, and acid addition salts thereof. The new compounds show valuable pharmacological properties, particularly on antithrombotic activity. Processes for the preparation of the new compounds, as well as pharmaceutical compositions containing them, are also objects of this invention,
机译:通式I (I)的化合物,其中n表示数字0或1,A表示亚甲基,亚乙烯基或亚乙基,可选地被低级烷基取代,B表示亚烷基,R1表示可选地取代的烷基,苯基R 2为萘基,萘基,环烷基或吡啶基,以及它们的酸加成盐。新化合物显示出有价值的药理特性,尤其是在抗血栓形成方面。制备新化合物的方法以及包含它们的药物组合物也是本发明的目的,

著录项

  • 公开/公告号AR230745A1

    专利类型

  • 公开/公告日1984-06-29

    原文格式PDF

  • 申请/专利权人 DR. KARL THOMAE G.M.B.H.;

    申请/专利号AR19820290035

  • 发明设计人

    申请日1982-07-21

  • 分类号C07D209/34;C07D215/26;

  • 国家 AR

  • 入库时间 2022-08-22 09:24:03

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