aromatiska, biocida foereningar, deras syntes och dess mellanprodukt, year innehaollande preparat samt anvaendni ng av (inom medicinen.

摘要

Compounds of the formula (I) CHEM or monomethyl or monoethyl ethers thereof, the compounds including their ethers containing no more than 28 carbon atoms in total, or esters or salts thereof; wherein Ar is selected from the group comprising: CHEM optionally substituted by one or two substituents which taken together contain not more than four carbon atoms in total and which are the same or different and are selected from halo; cyano; C1-3 alkyl or C1-3 alkoxy each optionally substituted by hydroxy or C1-2 alkoxy; halo substituted C1-2 alkyl or C1-2 alkoxy; a group S(O)nR5 wherein n is an integer 0, 1 or 2 and R6 is C1-2 alkyl optionally substituted by hydroxy or C1-2 alkoxy; or Ar is optionally substituted by a group NR6R7 containing not more than 5 carbon atoms wherein R6 and R7 are the same or different and each is a C1-3 alkyl group or NR6R7 forms a five or six membered heterocyclic ring optionally containing one or two additional hetero atoms; R1 is C1-3 alkyl substituted by hydroxy; R2 is hydrogen, C1-3 alkyl or hydroxymethyl; R3 and R4 are the same or different and each is hydrogen, methyl or ethyl; R1, R2, R3 and R4 taken together containing not more than five carbon atoms; or the group; CHEM wherein -@@@- is a five or six membered saturated carbocyclic ring containing two or three hydroxy groups; R8 is hydrogen, methyl or hydroxymethyl; R9 and R10 are the same or different and each is hydrogen or methyl; R11 is hydrogen, hydroxy, methyl or hydroxymethyl; R8, R9, R10, R11 and the -@@@- ring taken together containing less than seven carbon atoms which have biocidal, and particularly antitumour, activity are described as are methods for their preparation, their use in medicine and pharmaceutical formulations containing them.