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SUBSTITUTED IMIDAZO(2,1-B)THIAZOLES OR THIAZOLO(3,2-A)PYRIMIDINES AND ANTIINFLAMMATORY PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
SUBSTITUTED IMIDAZO(2,1-B)THIAZOLES OR THIAZOLO(3,2-A)PYRIMIDINES AND ANTIINFLAMMATORY PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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机译:取代的咪唑并(2,1-B)噻唑或噻唑并(3,2-A)嘧啶和包含它们的抗炎药
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摘要
Certain imidazothiazoles and thiazolopyrimidines have been found to prevent and inhibit the formation of granuloma tissue in animals. This result is accomplished by administering to the animal subject a therapeutically effective amount of a compound having the formula: ##STR1## wherein R is hydrogen or methyl, R' is hydrogen, lower alkyl or thioalkyl, carboxy methyl, or phenyl; R" is lower alkyl, 2-benzofuranyl, naphthyl, phenyl, or mono- or disubstituted phenyl. The hydrated precursors of certain of these compounds as well as the acid addition and quaternary salts of both the compounds and their hydrated precursors may be employed.
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