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OMEGA-AMINOALKOXYIMINOCYCLODODECANE DERIVATIVES,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
OMEGA-AMINOALKOXYIMINOCYCLODODECANE DERIVATIVES,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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机译:欧米诺-烷氧基亚氨基环十二烷衍生物,其制备及其组成的药物成分
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摘要
The invention relates to novel cyclododecane derivatives of the general formula IMAGE (I) wherein R1 and R2 represent independently from each other a hydrogen atom, a C1-6 alkyl group or a C3-8 cycloalkyl group, or R1 and R2 form together with the nitrogen atom to which they are attached a heterocyclic ring containing 4 to 7 carbon atoms and optionally a further heteroatom selected from the group consisting of oxygen, sulphur and nitrogen, said ring may be optionally substituted by a C1-3 alkyl or benzyl group; and A represents a C2-6 straight or branched alkylene chain, and optically active isomers, acid addition salts and quaternary ammonium derivatives thereof. The invention relates further to an analogous process for the preparation of said compounds, to pharmaceutical compositions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions. The cyclododecane derivatives of the invention possess valuable biological properties.
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