method for the manufacture of a pharmaceutical preparation and preparation of contraceptive operation on the basis of 2 - (halogeenfenyl) s triazolo (5.1 - (a) isochinoline derivatives and process for preparation of the usable 2 - (halogeenfenyl) s triazolo (5.1-a) isochinoline derivatives or the zuuradditiezouten thereof.

摘要

Triazolo-isoquinolines of formula (I) are new. (where R1 is Cl or F). (I) are prepd. by reacting 2-amino-1-(2H)-isoquinolone with an R1-substd. ethyl benzimidate, then cyclising the intermediate with base. (I) are contraceptives effective when administered after coitus or conception, and their abortion-inducing activity is not associated with other biological activities. They can be given orally or parenterally one or more times a month as necessary.