Process for the separation of enantiomers of 2,3,3a, 4,5,6-hexahydro-1H-indole-3,2,1-DENAFTYRIDINE 1.5, and the therapeutic application DE HEXAHYDROENANTIOMEREN THEREOF.

摘要

Enantiomers of the title compound of the formula: IMAGE which have hitherto not been characterised specifically, are isolated from their mixtures by preparing addition salts with an enantiomer of a chiral acid. The diastereoisomers obtained are separated by fractional crystallisation and then converted back to the form of the base or of a pharmaceutically acceptable acid addition salt. The enantiomers of the above named compound are useful in therapy as they possess an antianoxic activity.