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A process for the preparation of Derivatives of etanola - mine.

机译:一种制备艾塔诺拉衍生物的方法。

摘要

Method for obtaining Derivatives of etalnolamina acyl derivatives and their Salts and hydrolysable Alive ~ ~ Ain B, of formula (i), in which R r 1 and 2 are Hydrogen or Methyl; R r 3, 4 and 5 may be several radical R ; and N is 1 or 2.Consists in the reduction reaction of an oxo Group and / or a double bond and / or other reducible to a group R, 4, a compound of formula (ii), in which R 1 1 1, R 2, R 1 3 R 1 , 4, r R 1 1 5 r 1 6 and 7 may be several radical and the other symbols have the same meaning as in formula ( (i).The reduction takes place through Complex hydrides or by catalytic reduction in a Solvent alcanolico Lower, at temperatures between 0 and 20 C C. these compounds have applications for their pharmacological activity and / or antihiperglicemica antiobesity and / or anti-inflammatory and / or inhibitory Platelet aggregation.
机译:制备式(i)中的乙萘胺酰基衍生物及其盐和可水解的Alive Bin的衍生物的方法,其中R> r> 1和2是氢或甲基。 R> r> 3、4和5可以是多个基团。和N为1或2。包括氧代基团和/或双键和/或其他可还原为基团R> 4的式(ii)化合物的还原反应,其中R> 1 1> 1,R 2,R 1> 3> R 1>,> 4,r> R> 1 1> 5 r> 1 6和7可以是多个基团,其他符号的含义与在0至20℃之间的温度下,可通过络合氢化物或在溶剂醇低聚物中催化还原来进行还原。这些化合物因其药理活性和/或抗hiperglicemica肥胖症和//或抗炎和/或抑制血小板聚集。

著录项

  • 公开/公告号ES8308835A1

    专利类型

  • 公开/公告日1983-12-16

    原文格式PDF

  • 申请/专利权人 BEECHAM GROUP P.L.C.;

    申请/专利号ES19820513967

  • 发明设计人

    申请日1982-07-12

  • 分类号C07C91/06;A61K31/135;

  • 国家 ES

  • 入库时间 2022-08-22 09:06:30

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