Procedure for the synthesis of New Derivatives of cyano - Omega 1, Omega - aza - diphenyl alkane.

摘要

Method for obtaining Derivatives of cyano - Omega 1, Omega - aza - diphenyl alkane, of formula (i), in which R High R 2 R 3 High, High, high high R R 6, 7 and 8 High R are the same or different and represent Hydrogen Atoms.Halogen Atoms or hydroxyl groups; high 4 R is a linear or branched alkyl group; R High 5 is a hydrogen Atom or a radical alkyl with 1 to 4 carbon Atoms; and M and N are giaules or different and represent 2, 3 or 4, and their physiologically acceptable salts with acids.Consists in reacting an Omega - amino alkyl phenylacetonitrile, of formula (ii), in which R High 1 to 5 m high and R have the meanings mentioned above, with an aldehyde of formula (iii), in which R High 6 to 8 High N and R have the meanings given above, under condition Reducing ones.Application in the treatment of Functional disorders of the Cardiovascular System. * * formula.