Antibiotic PA-31088-IV, its salts with bases, a process for its manufacture, pharmaceutical compositions containing this antibiotic, streptomyces tokunonensis PA-31088 and its mutants

摘要

A new antibiotic having beta -lactamase inhibitory activity, PA-31088-IV, being useful as a medicament and a veterinary drug for inhibiting the growth of gram-positive and gram-negative phathogenic microorganisms and a process for preparing the same, being characterized by cultivating Streptomyces tokunonensis sp. nov. in a suitable medium and recovering PA-31088-IV from the cultured broth.