THERMOLYSIS OF 2-(3-ARYL-ISOXAZOL-5-YL)BENZOIC ACIDS, SALTS AND HALIDES FROM 3'-(ARYL)-SPIRO(ISOBENZOFURAN-1(3H),5'(4'H)ISOXAZOL)-3-ONES

摘要

A process for preparing 2-(3-Aryl-5-isoxazolyl)-benzoic acid having the formula CHEM wherein X and Y are independently selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, halo-lower-alkyl, phenoxyphenyl and cyano, respectively its salts or halides, which comprises treating 3 min -(Aryl)spiro-[isobenzofuran-1(3H), 5 min (4 min H)-isoxazol]-3-one having the formula CHEM with respectively, heat, a strong base or a reactive halide and water.