Automatic disintegration time measuring device for the pharmaceutical quality and production control of tablets and coated tablets

摘要

The invention relates to an automatic disintegration time measuring device for the pharmaceutical quality and production control of tablets and coated tablets, which comprises a basket-like frame (10) located in a beaker (70) provided with a volume of liquid for the vertical mounting of a number of glass tubes (30, 31) which are designed so as to be open on both ends and stand with their bottom openings on a bottom plate (11) designed like a screen plate, each glass tube (30, 31) receiving a test specimen (T) covered by a float (60) lying inside the glass tube and having vertical perforations or incisions on the outer edge, and a drive device (15) which moves the frame (10) with the glass tubes (30, 31) in the beaker (70) up and down in predetermined units of time, with such a design that not only can the time in disintegration tests of tablets be recorded automatically but moreover the accurate disintegration time can be read off simply and quickly and in which visual control on occurrence of turbidity of the test liquid is avoided, so that, in particular, even tablets with an enteric coating can be tested with regard to their disintegration without a great expenditure of time and without the need for a long observation time. IMAGE