SECRETION OF ACCURATELY TREATED HUMAN GROWTH HORMONE FOR BACILLUS COLI AND PSEUDOMONAS

摘要

The production of mature hGH In E. coli and Pseudomonas strains transformed by a plasmid which encodes pre hGH (comprising the signal polypeptide and the hormone itself) is described. These prokaryotes process the pre-hGH to cleave the signal sequence and, thereby, produce mature hGH.