A composition for use in the preparation of a Technetium-99m bone-scanning agent comprises a mixture of ethylene glycol-1,2-bisphosphonic acid or a non-toxic salt thereof together with a reducing agent for pertechnetate. Technetium-99m, as an aqueous solution of pertechnetate, is added to the composition to form a complex of Technetium-99m and the bisphosphonate. The complex is useful as a bonescanning agent and is rapidly taken up in bone to give scans of high definition.
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