AN AQUEOUS PHARMACEUTICAL COMPOSITION COMPRISING A MICELLAR SOLUTION OF LEVONANTRADOL OR N-METHYL-LEVONANTRADOL

摘要

A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also covered are pharmaceutically acceptable lyophile compositions prepared by the lyophilization of the aqueous micellar solutions. …??Levonantradol and N-methyllevonantradol are analgetic and anti-emetic agents.