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4-NITRO-1,2-HYDROCARBYL-PYRAZOLIDINES AND METHODS OF SYNTHESIS OF 4-AMINO ANALOGUES THEREFROM
4-NITRO-1,2-HYDROCARBYL-PYRAZOLIDINES AND METHODS OF SYNTHESIS OF 4-AMINO ANALOGUES THEREFROM
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机译:4-硝基-1,2-羟基-吡咯烷二酮及4-氨基类似物的合成方法
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摘要
4-Nitro-1,2-hydrocarbyl pyrazolidines are prepared by a novel route from 1,2-disubstituted hydrazines and 1,3-di-(secondary amino)-2-nitropropanes and reduced to the corresponding 4-amino-1,2-hydrocarbyl pyrazolidines, which latter compounds are intermediates in the preparation of certain pharmaceutical benzamides. The novel 4-nitro-1,2-hydrocarbyl pyrazolidines have the formula: IMAGE wherein R1 and R2 are selected from loweralkyl, lowercycloalkyl or phenyl-loweralkyl and may be the same or different.
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