interfenilen 8 - aza - 9 - diossotia - 11 - secoprostaglandine

摘要

Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins are prepared by the two-stage alkylation of the anion of a lower alkyl sulfonamide, R1SO2NH2, using first a compound of the formula: IMAGE and second, a compound of the formula: IMAGE The compounds produced have renal vasodilatory activity when administered orally and are therefore useful for treating patients with renal impairment.