The method of Spokane tin compounds sepam

摘要

Compds. of formula (I) and their salts are new (where R1 is H or lower alkyl; R2 is (1-methyl-1H-tetrazol-5-yl)thio; R3 is COOH; n is 2 or 3, or R2 is Y-substd. pyridinio and R3 is COO-; Y is H, CH2OH or CONH2). (I) have antibacterial activity, often higher than that of cefmenoxime and ceftazidime against Gram-negative and Gram-positive bacteria, and may be used as medicaments or animal feed bacteria.