1,7-dihydro-pyrrolo 3,4-e 1,4 diazepin -2 (3H) - one derivatives and the preparation process and antispasmodics, the purpose of the material as the material of the sedative

摘要

1,7-dihydro-pyrrolo[3,4-e][1,4]diazepin-2(3H)-one derivatives of the formula …CHEM… wherein R is (C1-4)alkyl, R1 stands for hydrogen, methyl, ethyl, phenyl, bromo, chloro or nitro, R2 is hydrogen or (C1-4)alkyl, R3 represents hydrogen, chloro, fluoro, bromo, trifluoromethyl and methoxy, and X is …CHEM… wherein n is zero or 1, or -NH-R4 wherein R4 represents a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, or phenyl group. …??The novel compounds are useful as anticonvulsant and anti-anxiety agents. …??Also encompassed by the present invention are the process for preparing the novel pyrrolodiazepines and the pharmaceutical compositions containing them.