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1-에틸-6-플루오로-1,4-디하이드로-7-(1-피페라지닐)-4-옥소퀴놀린-3-카르복실산의 The method
1-에틸-6-플루오로-1,4-디하이드로-7-(1-피페라지닐)-4-옥소퀴놀린-3-카르복실산의 The method
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机译:1-乙基-6-氟-1,4-二氢-7-(1-哌嗪基)-4-氧喹啉-3-羧酸的方法
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摘要
PT--78926 A 1-Ethyl 6-fluoro 1,4-dihydro 7-(1-piperazinyl) 4-oxo quinoline 3-carboxylic acid, of formula (I) is made by a process comprising two phases of reaction with the piperazine and a final phase in presence of an alkali metal hydroxide. The process requires lower quantities of piperazine and gives a pure product in increased yield compared with conventional processes.
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