5 - manufacturing methods of replaced prison Julie Dean

摘要

Racemic and optically active oxazolidine-2,4-diones of formula (I), and their salts are new, (where R is H, 1-4C alkanoyl, benzoyl, 2-4C carbalkoxy, 1-3C alkyl- 5-7C cycloalkyl-, and di(1-3C alkyl)- carbamoyl; R1 is (a) a group of formula (II)-(IV) (where R' is 1-4C alkyl or phenyl; R" is H or R'; X is halogen) (b) a group (V) (where Y is H, 1-3C alkoxy, Y' is H or 1-3C alkyl; Y" is H or halogen) (c) a group (VI or (VII) where Z' is H, halogen, or 1-3C alkoxy; Z" is H or halogen; (d) a group (VIII) where W is H or halogen on any position; n is 1 or 2; (e) a group (IX)-(XI) where Q is S or O; V is H or 1-3C alkyl; (f) a group (XII) or (XIII) attached through any position, where Y = O or S; X is H, halogen, methyl, phenyl, benzoyl or 1-3C alkoxy; X1 is H or CH3; X2 is H or halogen). Used as antihyperglycemic agents.