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Esters of mercaptoacyl - carnitines, for their preparation and their therapeutic uses, in particular in the treatment of poisoning and burns and as agents mucolytics
Esters of mercaptoacyl - carnitines, for their preparation and their therapeutic uses, in particular in the treatment of poisoning and burns and as agents mucolytics
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机译:巯基酰基肉碱的酯,用于其制备及其治疗用途,尤其是在中毒和烧伤的治疗中以及作为粘液溶解剂
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摘要
A novel class of esters of mercapto acyl-carnitines is disclosed, wherein the mercapto acyl radical is the radical of saturated mercapto acids having from 2 to 10 carbon atoms. These esters of mercapto acyl-carnitines are prepared e.g. by first preparing the corresponding ester of halogen acyl-carnitine and then substituting therein, by nucleophylic substitution, the -SH group for the halogen atom. These esters of mercapto acyl-carnitines are useful therapeutic agents, e.g. for the treatment of intoxications and burns, and as mucolytic agents.
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