This to prepare the 4 - hydroxy - 2 - methyl - 2h - 1,2 - benzothiazine preferably cannot, or substantially - 3 - (n - (2 - pyridinyl) -6-acetoxy-3,4-dihydro-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxamide) - 1,1 - dioxide, the phosphoric ester and the phosphoric ester obtained.

摘要

Method of preparation of 4 - hydroxy - 2 - methyl - 2h - 1,2 - benzo - thiazine - 3 - n - (2 - pyridyl) -6-acetoxy-3,4-dihydro-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxamide - 1,1 - dioxide, the phosphoric ester of formula i and ii, and the ester obtained br / (see appended drawing in bopi) & br / characterizes in that the n - methylation is carried out according to the method called "phase transfer catalysis. / p & & p & the compounds are useful in the application and present of the pharmacological anti inflammatory -