The acid (dimethyl - 2,6 diethoxycarbonyl - 3,5 dihydro - 1,4 pyridine -carboxamido - 4) - 2 glutaric acid and its disodium salt, and their method of preparation and their application of international application no.

摘要

2-(2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine-4-carboxamide) glutaric acid of formula I and its disodium salt of formula II IMAGE (I) IMAGE (II) Said acid is obtained from glutaminic acid and dimethyl 3,5-diethoxycarbonyl-1,4-dihydroisonicotic acid. For obtaining disodium salt, said acid is reacted with a caustic soda solution. These compounds possess antiarrhythmic activity.