5-HYDROXYL-L-TRYPTOPHAN-PRODUCING MICROORGANISM AND PREPARATION OF 5-HYDROXY-L-TRYPTOPHAN USING SAID MICROORGANISM

摘要

PURPOSE:To provide the titled microbial strain resistant to 5-fluorotryptophan, requiring anthranylic acid, and capable of producing the culture liquid containing 5-hydroxy-L-tryptophan in high concentration from a culture medium containing 5-hydroxy-anthranylic acid in high concentration. CONSTITUTION:Bacillus amyloliquefaciens SD-53 (FERM-P No.7773) resistant to 5-fluorotryptophan, requiring anthranylic acid, and capable of producing 5-hydroxy-L-tryptophan. There is no accumulation of L-tryptophan which is difficult to be separated from 5-hydroxy-L-tryptophan, and accordingly, the objective 5- hydroxy-L-tryptophan can be prepared in high yield.