PROCEDURE FOR THE PREPARATION OF GLYCOSYL FLUORIDES IN A STEP AND SEPARATION OF HYDROGEN FLUORIDE

摘要

A process for the single-stage preparation of glycosyl fluorides by dissolving saccharides in liquid hydrogen fluoride and evaporating the hydrogen fluoride, wherein the resulting glycosyl fluoride is isolated in such a way that, when the evaporation of the hydrogen fluoride is started at a relatively high temperature, in general at -20 DEG to +20 DEG C., the evaporation is effected at a high evaporation rate or, when a low evaporation rate is used at the start of the evaporation, a sufficiently low temperature is set, in general -80 DEG C. to -30 DEG C.