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4,5-dihydro-6H- (1,3-dioxolo) (3,4) naphtho (1,2-b) pyrans and to their preparation and use

机译:4,5-二氢-6H-(1,3-二氧戊环)(3,4)萘并(1,2-b)吡喃及其制备和使用

摘要

Compounds of the formula IMAGE in which R1 and R2 independently of one another denote hydrogen, lower alkyl or aryl or, taken together, denote lower alkylene, R3 and R4 independently of one another denote hydrogen, lower alkyl or aryl or, taken together, denote lower alkylene, and the ring A has no additional substituents or is additionally substituted by lower alkyl, lower alkoxy and/or halogen, are active in retrovirus-induced Rauscher leukaemia of the mouse and can therefore be used therapeutically, for example in the control of immune diseases or autoimmune diseases likewise caused by retroviruses.
机译:的化合物,其中R 1和R 2彼此独立地表示氢,低级烷基或芳基,或一起表示低级亚烷基,R 3和R 4彼此独立地表示氢,低级烷基或芳基或一起,表示低级亚烷基,并且环A没有另外的取代基或另外被低级烷基,低级烷氧基和/或卤素取代,在逆转录病毒诱导的小鼠劳氏白血病中有活性,因此可以用于治疗,例如控制由逆转录病毒引起的免疫疾病或自身免疫疾病。

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