A method for producing a protein comprising the proteins encoded by the coding region of the PreS1-PreS2-S protein of the hepatitis B virus surface antigen and the recombinant DNA vectors and contaminants and mammalian cells used in the method

摘要

Bacterial plasmids carrying the PreS1-PreS2-S protein coding region, but lacking sequences encoding the hepatitis B core antigen, which are used for transfection of eukaryotic cell lines for the production of particles containing polypeptides encoded by the PreS1-PreS2-S protein coding region.