PROCESS FOR PREPARING 1-PHENYL-1,8-NAPHTHYRIDINE AND 1-PHENYL-5-AZA-1,8-NAPHTHYRIDINE DERIVATIVES

摘要

1,8-Naphthyridine and 1,5,8-azanaphthyridine derivs. of formula (I) and their pharmaceutically acceptable acid addn. salts are prepd. In (I), X=CH or N; Y=H, hydroxy, benzyloxy, halo, C1-6 alkoxy, -S(0)m- [m= 0 or 1 or -COOA[A= H or C1-6,alkyl ; Z= H, hydroxy, halo, C1-6 alkoxy or C2-6 alkanoyloxy; R1 =C2-10 alkenyl, C3-7 cycloalkyl or furyl; R2=H, C1-6 alkanoyl or C2-6 hydroxyalkyl. (I) are useful in the treatment of allergic diseases.