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NEW DERIVATIVES OF 2,4,6-TRIIODO-ISOPHTHALIC ACID,PROCESSES FOR THEIR SYNTHESIS AND X-RAY CONTRASTING MATERIALS CONTAINING THESE
NEW DERIVATIVES OF 2,4,6-TRIIODO-ISOPHTHALIC ACID,PROCESSES FOR THEIR SYNTHESIS AND X-RAY CONTRASTING MATERIALS CONTAINING THESE
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机译:2,4,6-三碘-异邻苯二甲酸的新衍生物,其合成方法和包含这些的X射线对比材料
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摘要
Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-( alpha -hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.
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