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DERIVATIVES OF 7-(2-(2-AMINO-4-THIAZOLYL)-2-OXYIMINO-ACETAMIDO)3-PYRIDINIUM THIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DERIVATIVES OF 7-(2-(2-AMINO-4-THIAZOLYL)-2-OXYIMINO-ACETAMIDO)3-PYRIDINIUM THIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID,THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
The present invention relates to cephalosporins of general formula: IMAGE in which: R1 is H or CH3, R2 is CH3, or R1 and R2 taken together form a 1,3-propylene group, R3 is lower alkyl, alkenyl, alkynyl or CH2COO alkyl, R4 is H or OH, the S being bonded to the pyridine ring in 2 or 4 position, A is H or cation or ester or hemiacetal which is easily hydrolyzable, and X is a derivative of a mineral or organic acid. The invention also relates to a process for preparing these new cephalosporins and to the drugs containing said cephalosporins.
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