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acetilsalicilato 2 or metossi analgesic antipyretic activity fenossi ethanol and inflammation and its preparation method
acetilsalicilato 2 or metossi analgesic antipyretic activity fenossi ethanol and inflammation and its preparation method
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机译:扑热息痛2或美托西止痛解热药芬诺西乙醇与炎症反应及其制备方法
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摘要
2-(2-Methoxy -phenoxy)ethyl acetyl salicylate of formula (I) is new. Analgesic, antipyretic, antiinflammatory, and bronchosecretolytic agent, which is used to treat fevers, colds, rheumatic and neuralgia and esp. catarrhal and respiratory troubles associated with inflammation, fever, pain and tracheo-broncho-pulmonary troubles. (I) has lower toxicity than acetylsalicylic acid, superior analgesic, antipyretic and antiinflammatory activity than acetylsalicylic acid and a bronchosecretolytic activity comparable with that of gaiacol derivs. Activity and toxicity (LD50 of (I) oral in rats is 2934 mg/kg.; aspirin LD50 is 1400 mg/Kg).
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