A process for the preparation of N - (3-methoxy-3-oxopropyl Uncle - - 1) - N - (4 - fenilciclohexil) - Wisteria.

摘要

Process for the preparation of N - (3 - Man - 1 - 3-methoxy-3-oxopropyl) - N - (4 - fenilciclohexil) - Wisteria.Includes: 4 - fenilciclohexanona) REACT with an ester of Glycine in the presence of a Lewis base and the product thus obtained hidrogenir and reacting the product of (a) with an Acid chloride chrcoc1 Sch2 Formula R1, to produce a compound of formula (i) wherein R is H or alqui The inferior and R1 is H or benzoyl.They are inhibitors of the Angiotensin converting Enzyme decaptido.