首页> 外国专利> A method for producing cells whose antigen-specific humoral immune responses have been Modulated.

A method for producing cells whose antigen-specific humoral immune responses have been Modulated.

机译:一种产生已调节了抗原特异性体液免疫应答的细胞的方法。

摘要

Method for producing cells whose Antigen specific humoral immune responses have been Modulated.Comprising: (a) introduce a guanine that is not electrically charged functionality at Ambient temperature and pressure 8 Substituent in position 8 with a Union Sulphide has an Inductive effect of the acceptance of electrons above the H and less than 15 Atoms to form a Rivate guanine replaced as 8 - 8 - 8 - mercaptoguanosina bromoguanosina and others; (b) Link.N 9 of the derivative obtained in (a) with position 1 of an Aldose to C 5 6 of formula (i) at Ambient temperature and pressure.Still other Hydroxy and H: R1; R2 and R3 and R4 H other Hydroxy methoxy Methyl; and N is 0 OR 1; (c) to combine the product b) with an amount of a physiologically tolerable Diluent Vehicle; and (d) the product REACT with c) a cell to modulate immune response humoral ESP Ecifica Antigen.
机译:产生已调节抗原特异性体液免疫反应的细胞的方法,包括:(a)在环境温度和压力8下引入不带电荷功能的鸟嘌呤,在8位取代有硫磺,具有诱导接受电子在H之上且少于15个原子形成形成鸟嘌呤的Rivate鸟嘌呤,被取代为8-8-mercaptoguanosina bromoguanosina等; (b)在环境温度和压力下,将(a)中获得的衍生物的N 9与醛糖的位置1连接到式(i)的C 5 6上。 R 2和R 3和R 4 H为羟基甲氧基甲基; N为0或1; (c)将产品b)与一定量的生理上可稀释的稀释剂混合使用; (d)产物与c)反应以调节免疫反应的体液ESP Ecifica抗原。

著录项

  • 公开/公告号ES8601301A1

    专利类型

  • 公开/公告日1986-02-16

    原文格式PDF

  • 申请/专利权人 SCRIPPS CLINIC & RESEARCH FOUNDATION;

    申请/专利号ES19830527138

  • 发明设计人

    申请日1983-11-08

  • 分类号C12N1/36;

  • 国家 ES

  • 入库时间 2022-08-22 07:37:42

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